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Peptide record

TPDB65683

4R-16 Tumor-homing Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB65683
4R-16
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 9-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
N-terminal: fluorescent reagent FPI774
Sequence
CMPKRPSSC
Physicochemical Analysis
C39H69N13O12S3
ANDEQGHILFTWYV
CPS
1008.24
9.15
2
0
1
+2
2.25
-0.700
0.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
12.40
4
Residue Composition
number
0
A
1
R
0
N
0
D
2
C
0
E
0
Q
0
G
0
H
0
I
0
L
1
K
1
M
0
F
2
P
2
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 1 M: 1 F: 0 P: 2 S: 2 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
9
C39H69N13O12S3
1008.24
9.15
+2
2.25
-0.700
fluorescent reagent FPI774
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting
Lung tumor, Pancreatic cancer, Colorectal cancer, biliary tract cancer, gallbladder cancer, leukemic cell.
VGF receptor, MMP

Source & Reference

TumorHoPe2.0
TumorHoPe2
Cancer cell-targeting peptide and use thereof
2019
US 10370410 B2
US 10370410 B2

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
NCI/NIH mice, wild type C57BL/6N mouse
Phage Display library
T7 CX7C phage library
Fluoresceine
Additional Detail Fields 3 fields
Fluoresceine
NCI/NIH mice, wild type C57BL/6N mouse
T7 CX7C phage library