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Peptide record

TPDB65678

PD-L1Pep-1 Tumor-homing Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB65678
PD-L1Pep-1
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 9-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
N-terminal: Fluorescein isothiocyanate (FITC), biotin, Flamma 675 near-infrared (NIR) fluorescent dye
Sequence
CLQKTPKQC
Physicochemical Analysis
C43H77N13O13S2
ARNDEGHIMFSWYV
CQK
1048.28
9.11
2
0
1
+2
2.69
-0.922
43.33
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
11.92
5
Residue Composition
number
0
A
0
R
0
N
0
D
2
C
0
E
2
Q
0
G
0
H
0
I
1
L
2
K
0
M
0
F
1
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 2 G: 0 H: 0 I: 0 L: 1 K: 2 M: 0 F: 0 P: 1 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
9
C43H77N13O13S2
1048.28
9.11
+2
2.69
-0.922
Fluorescein isothiocyanate (FITC), biotin, Flamma 675 near-infrared (NIR) fluorescent dye
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing

Source & Reference

TumorHoPe2.0
TumorHoPe2
Phage display-identified PD-L1-binding peptides reinvigorate T-cell activity and inhibit tumor progression
2020
Gurung S et al. Biomaterials.2020 Jul:247:119984

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
EK 293T (human embryonic kidney), MDA-MB231, MCF-7 (human breast tumor), CT26 (mouse colon tumor) cells
Balb/c mice
Phage display library
T7 phage / CX7C peptide library
Doxorubicin, Fluorescein isothiocyanate (FITC), biotin, Flamma 675 near-infrared (NIR) fluorescent dye
Additional Detail Fields 4 fields
Doxorubicin, Fluorescein isothiocyanate (FITC), biotin, Flamma 675 near-infrared (NIR) fluorescent dye
EK 293T (human embryonic kidney), MDA-MB231, MCF-7 (human breast tumor), CT26 (mouse colon tumor) cells
Balb/c mice
T7 phage / CX7C peptide library