Peptide record

TPDB65674

Tumor-homing Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB65674
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 9-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
CLKADKAKC
Physicochemical Analysis
C40H74N12O12S2
RNEQGHIMFPSTWYV
K
979.22
9.08
3
1
3
+2
2.82
-0.311
65.56
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
12.77
2
Residue Composition
number
2
A
0
R
0
N
1
D
2
C
0
E
0
Q
0
G
0
H
0
I
1
L
3
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 1 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
9
C40H74N12O12S2
979.22
9.08
+2
2.82
-0.311
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting
Breast cancer
NRP-1

Source & Reference

TumorHoPe2.0
TumorHoPe2
SPECT and near-infrared fluorescence imaging of breast cancer with a neuropilin-1-targeting peptide
2014
Feng GK et al. J Control Release. 2014 Oct 28:192:236-42

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
MDA-MB-231, T-1, MDA-MB-435, MCF-7
Phage display library
T7phage/(CX7C) peptide library
Additional Detail Fields 2 fields
MDA-MB-231, T-1, MDA-MB-435, MCF-7
T7phage/(CX7C) peptide library