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Peptide record

TPDB65669

CREKA Tumor-homing Peptides modified_plain modified
19 amino acids
Basic Information
3D PDB MODEL
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TPDB65669
CREKA
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
modified_plain
Yes
A 19-aa modified tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
CLBCREKAKKLFKKILKKL-NH2
Physicochemical Analysis
C101H184N28O21S2
NDQGHMPSTWYV
K
2190.87
10.65
8
1
7
+7
5.43
-0.316
107.89
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
5.71
2
Residue Composition
number
1
A
1
R
0
N
0
D
2
C
1
E
0
Q
0
G
0
H
1
I
4
L
7
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 2 E: 1 Q: 0 G: 0 H: 0 I: 1 L: 4 K: 7 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
19
C101H184N28O21S2
2190.87
10.65
+7
5.43
-0.316
Amide
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor vessel
Homing
Breast cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Identification of BP16 as a non-toxic cell-penetrating peptide with highly efficient drug delivery properties
2014
Marta Soler et al. Org Biomol Chem. 2014 Mar 14, 12, 1652-1663

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
breast adenocarcinoma MCF-7, pancreas adenocarcinoma CAPAN-1, mouse embryonic fibroblast 3T3 cell line
Phage display library
CECMEL11 peptide library
BP329 (CLB-KKLFKKILKKL)
Additional Detail Fields 3 fields
BP329 (CLB-KKLFKKILKKL)
breast adenocarcinoma MCF-7, pancreas adenocarcinoma CAPAN-1, mouse embryonic fibroblast 3T3 cell line
CECMEL11 peptide library