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Peptide record

TPDB65665

4R-3 Tumor-homing Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB65665
4R-3
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 9-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
N-terminal: fluorescent reagent FPI774
Sequence
CKSRKDGAC
Physicochemical Analysis
C36H66N14O13S2
NEQHILMFPTWYV
CK
967.13
9.11
3
1
1
+2
3.51
-1.133
11.11
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
12.92
3
Residue Composition
number
1
A
1
R
0
N
1
D
2
C
0
E
0
Q
1
G
0
H
0
I
0
L
2
K
0
M
0
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 1 C: 2 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 2 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
9
C36H66N14O13S2
967.13
9.11
+2
3.51
-1.133
fluorescent reagent FPI774
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting
Lung tumor, Pancreatic cancer, Colorectal cancer, biliary tract cancer, gallbladder cancer, leukemic cell.
VGF receptor, MMP

Source & Reference

TumorHoPe2.0
TumorHoPe2
Cancer cell-targeting peptide and use thereof
2019
US 10370410 B2
US 10370410 B2

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
NCI/NIH mice, wild type C57BL/6N mouse
Phage Display library
T7 CX7C phage library
Fluoresceine
Additional Detail Fields 3 fields
Fluoresceine
NCI/NIH mice, wild type C57BL/6N mouse
T7 CX7C phage library