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Peptide record

TPDB65642

Tumor-homing Peptides standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB65642
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 13-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
CGFECVRQCPERC
Physicochemical Analysis
C60H96N20O19S4
ANDHILKMSTWY
C
1529.79
6.14
2
2
2
-0
4.68
-0.346
22.31
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
250
16.34
5
Residue Composition
number
0
A
2
R
0
N
0
D
4
C
2
E
1
Q
1
G
0
H
0
I
0
L
0
K
0
M
1
F
1
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 4 E: 2 Q: 1 G: 1 H: 0 I: 0 L: 0 K: 0 M: 0 F: 1 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
13
C60H96N20O19S4
1529.79
6.14
-0
4.68
-0.346
Evidence Records 2 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor vasculature
Targeting
Lung cancer
membrane dipeptidase (MDP)

Source & Reference

TumorHoPe2.0
TumorHoPe2
Protease inhibitor:protease sensitive expression system, composition and methods for improving the therapeutic activity and specificity of proteins delivered by bacteria
2022
US 11219671 B1
US 11219671 B1

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Salmonella typhimurium
Phage display library
Ph.D-7 Phage Display
Evidence 2 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell, Tumor vessel, Tumor stem cell, Endothelial cell, Epithelial cell, Dendritic cell
Homing
Lung cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Methods and compositions using peptides and proteins with C-terminal elements
2019
US 10370245 B2
US 10370245 B2

Other

PPC-1, PC-3, Du-145, 4T1, MIA PaCa-2, PDAC1.3, B16F10, M21, and MDA-MB-435 cell line
BALB/c athymic nude mice
Phage Display library
T7 phage display library
nanoparticles, nanoworms, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)2000 DSPE-PEG2000-maleimide]
Additional Detail Fields 4 fields
nanoparticles, nanoworms, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)2000 DSPE-PEG2000-maleimide]
PPC-1, PC-3, Du-145, 4T1, MIA PaCa-2, PDAC1.3, B16F10, M21, and MDA-MB-435 cell line
Salmonella typhimurium BALB/c athymic nude mice
Ph.D-7 Phage Display T7 phage display library