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Peptide record

TPDB65632

RGD peptide Tumor-homing Peptides standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB65632
RGD peptide
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 16-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
CCGPDGRDGRDGRDGR
Physicochemical Analysis
C61H102N28O25S2
ANEQHILKMFSTWYV
G
1691.77
6.24
4
4
0
-0
8.18
-1.912
0.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
7.39
2
Residue Composition
number
0
A
4
R
0
N
4
D
2
C
0
E
0
Q
5
G
0
H
0
I
0
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 4 C: 2 E: 0 Q: 0 G: 5 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
16
C61H102N28O25S2
1691.77
6.24
-0
8.18
-1.912
RGD
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell and vascular endotherial cell
Targeting
Lung tumor
αVβ3 integrin

Source & Reference

TumorHoPe2.0
TumorHoPe2
An artificial metalloenzyme for catalytic cancer-specific DNA cleavage and operando imaging
2020
Liang Gao et al. Sci Adv. 2020 Jul 15 6(29):eabb1421.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
A549 human lung cancer cells
BALB/c nude mice
Synthetic
Copper cluster, Bovine serum albumin (BSA)
Additional Detail Fields 3 fields
Copper cluster, Bovine serum albumin (BSA)
A549 human lung cancer cells
BALB/c nude mice