Back to search

Peptide record

TPDB65621

Tumor-homing Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB65621
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 9-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
CAKSKNRDC
Physicochemical Analysis
C38H69N15O14S2
EQGHILMFPTWYV
CK
1024.18
9.11
3
1
1
+2
3.92
-1.478
11.11
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
12.20
4
Residue Composition
number
1
A
1
R
1
N
1
D
2
C
0
E
0
Q
0
G
0
H
0
I
0
L
2
K
0
M
0
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 1 D: 1 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 2 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
9
C38H69N15O14S2
1024.18
9.11
+2
3.92
-1.478
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell, Endothelial cell
Homing
Triple negative Breast cancer
Constitutive androstane receptor (CAR)

Source & Reference

TumorHoPe2.0
TumorHoPe2
Compositions containing a pharmacophore with selectivity to diseased tissue and methods of making same
2023
US 11642391 B2
US 11642391 B2

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
MDA-MB-231 breast cancer cell line
11 weeks old, female athymic nude mice, male Sprague-Dawley rats (300-330 g, 10 weeks old)
Synthetic
fluorescamine (FAM)
Additional Detail Fields 3 fields
fluorescamine (FAM)
MDA-MB-231 breast cancer cell line
11 weeks old, female athymic nude mice, male Sprague-Dawley rats (300-330 g, 10 weeks old)