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Peptide record

TPDB65619

T1 Tumor-homing Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB65619
T1
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 12-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
AYPQKFNNNFMS
Physicochemical Analysis
C66H93N17O19S1
RDCEGHILTWV
N
1460.63
9.74
1
0
5
+1
-0.19
-1.025
8.33
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
1490
102.01
6
Residue Composition
number
1
A
0
R
3
N
0
D
0
C
0
E
1
Q
0
G
0
H
0
I
0
L
1
K
1
M
2
F
1
P
1
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 3 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 0 K: 1 M: 1 F: 2 P: 1 S: 1 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
12
C66H93N17O19S1
1460.63
9.74
+1
-0.19
-1.025
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting
Melanoma

Source & Reference

TumorHoPe2.0
TumorHoPe2
Evolutionary selection of personalized melanoma cell/tissue dual-homing peptides for guiding bionanofibers to malignant tumors
2018
Yang M et al. Chem Commun (Camb). 2018 Feb 8 54(13):1631-1634.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
A375, HEM
BALB/c mice (female, 4-6 weeks old)
Phage Display Library
M16
Pyropheophorbid-a (PPa)
Additional Detail Fields 4 fields
Pyropheophorbid-a (PPa)
A375, HEM
BALB/c mice (female, 4-6 weeks old)
M16