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Peptide record

TPDB65610

Peptide 3 Tumor-homing Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB65610
Peptide 3
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 12-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
C-terminal: (KKKK) as a linker
Sequence
ASEWQHRYMFEF
Physicochemical Analysis
C76H99N19O20S1
NDCGILKPTV
EF
1630.80
5.30
2
2
6
-1
1.07
-0.992
8.33
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
6990
428.62
3
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
2
E
1
Q
0
G
1
H
0
I
0
L
0
K
1
M
2
F
0
P
1
S
0
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 2 Q: 1 G: 0 H: 1 I: 0 L: 0 K: 0 M: 1 F: 2 P: 0 S: 1 T: 0 W: 1 Y: 1 V: 0
Chemical Descriptors
12
C76H99N19O20S1
1630.80
5.30
-1
1.07
-0.992
(KKKK) as a linker
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting
osteosarcoma

Source & Reference

TumorHoPe2.0
TumorHoPe2
Enhancement of T cell infiltration via tumor-targeted Th9 cell delivery improves the efficacy of antitumor immunotherapy of solid tumors
2022
Tao Chen et al. Bioact Mater. 2022 Dec 5:23:508-523.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
K7M2, HOS, 3T3, LLC, K7M2-Luci-OVA, K7M2- mCherry, HOS-Luci cell line
Female Balb/c (5-to-8 week-old) mice, Immune compromised Nod/SCID mice (5- to-8 week-old), DO11.10 mice, B6-G/R mice
Phage display library
Ph.D.-12 phage display peptide library
Cy5.5
Additional Detail Fields 4 fields
Cy5.5
K7M2, HOS, 3T3, LLC, K7M2-Luci-OVA, K7M2- mCherry, HOS-Luci cell line
Female Balb/c (5-to-8 week-old) mice, Immune compromised Nod/SCID mice (5- to-8 week-old), DO11.10 mice, B6-G/R mice
Ph.D.-12 phage display peptide library