Back to search

Peptide record

TPDB65599

SKLG Tumor-homing Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB65599
SKLG
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 12-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
AGRGRLVRSKLG
Physicochemical Analysis
C53H100N22O14
NDCEQHIMFPTWY
RG
1269.52
12.71
4
0
4
+4
2.36
-0.483
97.50
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
1
A
3
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
0
I
2
L
1
K
0
M
0
F
0
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 2 K: 1 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
12
C53H100N22O14
1269.52
12.71
+4
2.36
-0.483
CendR
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell, Tumor vessel
Homing
Glioblastoma

Source & Reference

TumorHoPe2.0
TumorHoPe2
Protease-activated CendR peptides targeting tenascin-C: mitigating off-target tissue accumulation
2024
Allan Tobi et al. Drug Deliv Transl Res. 2024 Jul 16 14(10):2945–2961

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
WT-GBM, VEGF-KO-GBM cell line, NCH421k cells
Female Athymic nude mice
Phage Display Library
FAM-labeled
Additional Detail Fields 3 fields
FAM-labeled
WT-GBM, VEGF-KO-GBM cell line, NCH421k cells
Female Athymic nude mice