Peptide record

TPDB65598

PL3uCendR Tumor-homing Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB65598
PL3uCendR
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 15-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
AGRGRLVRSAGGSVA
Physicochemical Analysis
C57H104N24O18
NDCEQHIKMFPTWY
G
1413.60
12.70
3
0
6
+3
1.80
0.060
84.67
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
3
A
3
R
0
N
0
D
0
C
0
E
0
Q
4
G
0
H
0
I
1
L
0
K
0
M
0
F
0
P
2
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 3 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
15
C57H104N24O18
1413.60
12.70
+3
1.80
0.060
CendR
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell, Tumor vessel
Homing
Glioblastoma

Source & Reference

TumorHoPe2.0
TumorHoPe2
Protease-activated CendR peptides targeting tenascin-C: mitigating off-target tissue accumulation
2024
Allan Tobi et al. Drug Deliv Transl Res. 2024 Jul 16 14(10):2945–2961

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
WT-GBM, VEGF-KO-GBM cell line, NCH421k cells
Female Athymic nude mice
Phage Display Library
FAM-labeled
Additional Detail Fields 3 fields
FAM-labeled
WT-GBM, VEGF-KO-GBM cell line, NCH421k cells
Female Athymic nude mice