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Peptide record

TPDB65597

PL3 Tumor-homing Peptides standard
8 amino acids
Basic Information
3D PDB MODEL
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TPDB65597
PL3
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 8-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
AGRGRLVR
Physicochemical Analysis
C36H69N17O9
NDCEQHIKMFPSTWY
R
884.05
12.70
3
0
3
+3
1.79
-0.562
97.50
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
1
A
3
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
0
I
1
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
8
C36H69N17O9
884.05
12.70
+3
1.79
-0.562
CendR
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell, Tumor vessel
Homing
Glioblastoma
NRP-1

Source & Reference

TumorHoPe2.0
TumorHoPe2
Protease-activated CendR peptides targeting tenascin-C: mitigating off-target tissue accumulation
2024
Allan Tobi et al. Drug Deliv Transl Res. 2024 Jul 16 14(10):2945–2961

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
WT-GBM, VEGF-KO-GBM cell line, NCH421k cells
Female Athymic nude mice
Phage Display Library
FAM-labeled
Additional Detail Fields 3 fields
FAM-labeled
WT-GBM, VEGF-KO-GBM cell line, NCH421k cells
Female Athymic nude mice