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Peptide record

TPDB65595

Tumor-homing Peptides standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB65595
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 19-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
C-terminal: Amidation N-terminal: Acetylation
Sequence
Ac-AGGCALPGSLAPLLCCTSL-NH2
Physicochemical Analysis
C74H127N19O23S3
RNDEQHIKMFWYV
L
1747.12
5.09
0
0
8
-0
-2.70
1.326
118.42
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
125
7.15
6
Residue Composition
number
3
A
0
R
0
N
0
D
3
C
0
E
0
Q
3
G
0
H
0
I
5
L
0
K
0
M
0
F
2
P
2
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 0 C: 3 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 5 K: 0 M: 0 F: 0 P: 2 S: 2 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
19
C74H127N19O23S3
1747.12
5.09
-0
-2.70
1.326
Amidation
Acetylation
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting
Breast cancer
HER2

Source & Reference

TumorHoPe2.0
TumorHoPe2
Preparation and In Vitro and In Vivo Characterization of the Tumor-specific Antigen-derived Peptide as a Potential Candidate for Targeting Human Epidermal Growth Factor Receptor 2-positive Breast Carcinomas
2018
Subhani M Okarvi et al. Anticancer Res. 2018 May 38(5):2823-2830.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
HER2-positive (SKBR3) and ER-positive (MCF7 and T47D), MDA-MB-231 (HER2-negative) breast cancer cell line
Synthetic
(SPECT) imaging probe
Additional Detail Fields 2 fields
(SPECT) imaging probe
HER2-positive (SKBR3) and ER-positive (MCF7 and T47D), MDA-MB-231 (HER2-negative) breast cancer cell line