Back to search

Peptide record

TPDB65577

Tumor-homing Peptides standard
7 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB65577
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 7-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
C-terminal: D-cysteine N-terminal: D-cysteine
Sequence
ADGREGF
Physicochemical Analysis
C31H46N10O12
NCQHILKMPSTWYV
G
750.77
4.07
1
2
2
-1
2.78
-1.100
14.29
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
1
A
1
R
0
N
1
D
0
C
1
E
0
Q
2
G
0
H
0
I
0
L
0
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 1 C: 0 E: 1 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
7
C31H46N10O12
750.77
4.07
-1
2.78
-1.100
D-cysteine
D-cysteine
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting
Bladder cancer
ανβ3 integrin

Source & Reference

TumorHoPe2.0
TumorHoPe2
Bladder cancer specific ligand peptides
2015
US 8946379 B2
US 8946379 B2

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Human bladder cancer cell line 5637
Athymic nude mice
Synthetic/ Recombinant
Cy5.5
At 5th position, D-amino acids
Additional Detail Fields 3 fields
Cy5.5
Human bladder cancer cell line 5637
Athymic nude mice