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Peptide record

TPDB65572

Tumor-homing Peptides standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB65572
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 10-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
ACGLSGLGVA
Physicochemical Analysis
C35H62N10O12S1
RNDEQHIKMFPTWY
G
847.00
5.33
0
0
5
-0
-1.47
1.590
127.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
2
A
0
R
0
N
0
D
1
C
0
E
0
Q
3
G
0
H
0
I
2
L
0
K
0
M
0
F
0
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 2 K: 0 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
10
C35H62N10O12S1
847.00
5.33
-0
-1.47
1.590
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell, vascular endotherial cell
Targeting
Malignant Gliomas

Source & Reference

TumorHoPe2.0
TumorHoPe2
Mammary-Derived Growth Inhibitor Targeting Peptide-Modified PEG-PLA Nanoparticles for Enhanced Targeted Glioblastoma Therapy
2015
Feng X et al. Bioconjug Chem. 2015 Aug 19 26(8):1850-61

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
U87 - MG glioblastoma cell, HUVEC
Glioma bearing Balb/c mice
Synthetic
Paclitaxel (PTX)
Additional Detail Fields 3 fields
Paclitaxel (PTX)
U87 - MG glioblastoma cell, HUVEC
Glioma bearing Balb/c mice