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Peptide record

TPDB65570

pHLIP Tumor-homing Peptides standard
36 amino acids
Basic Information
3D PDB MODEL
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TPDB65570
pHLIP
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 36-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
AAEQNPIYWARYADWLFTTPLLLLDLALLVDADEGT
Physicochemical Analysis
C191H285N43O56
CHKMS
L
4079.62
3.32
1
6
21
-5
-0.35
0.281
122.22
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
13980
342.68
7
Residue Composition
number
6
A
1
R
1
N
4
D
0
C
2
E
1
Q
1
G
0
H
1
I
8
L
0
K
0
M
1
F
2
P
0
S
3
T
2
W
2
Y
1
V
Amino Acid Distribution
A: 6 R: 1 N: 1 D: 4 C: 0 E: 2 Q: 1 G: 1 H: 0 I: 1 L: 8 K: 0 M: 0 F: 1 P: 2 S: 0 T: 3 W: 2 Y: 2 V: 1
Chemical Descriptors
36
C191H285N43O56
4079.62
3.32
-5
-0.35
0.281
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting
αv integrin

Source & Reference

TumorHoPe2.0
TumorHoPe2
Genetic Encoding of Targeted Magnetic Resonance Imaging Contrast Agents for Tumor Imaging
2020
Schuerle S et al. ACS Synth Biol. 2020 Feb 21 9(2):392-401.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
MDA-MB-435S, LS174T
Female nude mice bearing LS174T flank tumors
Synthetic
mamC gene
Additional Detail Fields 3 fields
mamC gene
MDA-MB-435S, LS174T
Female nude mice bearing LS174T flank tumors