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Peptide record

TPDB64975

Glutathione Oxidized Glutathione Blood-Brain Barrier Umami Selfassembly standard
3 amino acids
Basic Information
3D PDB MODEL
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TPDB64975
Glutathione Oxidized Glutathione
Blood-Brain Barrier Umami Selfassembly
Delivery and barrier-penetrating peptides Food sensory peptides Self-assembling and biomaterial peptides
Peptipedia Tastepeptides-Meta SAPdb
standard
No
A 3-aa standard natural multi-activity (Blood-Brain Barrier, Umami, and Selfassembly) peptide sequence curated from Peptipedia, Tastepeptides-Meta, and SAPdb, with an available 3D structural model.
Sequence
ECG
Physicochemical Analysis
C10H17N3O6S1
ARNDQHILKMFPSTWYV
CEG
307.32
3.29
0
1
0
-1
1.79
-0.467
0.00
Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
1
C
1
E
0
Q
1
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 1 E: 1 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
3
C10H17N3O6S1
307.32
3.29
-1
1.79
-0.467
Linear
Similarity
Glu-Cys-Gly
O=C(NCC(=O)O)C(NC(=O)C(N)CCC(=O)O)CS
Self-Assembly Information 2 records
Record 1 Selfassembly

Source

11457225
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Hydrogel Gel consists of fibril structure
temperature: 60 °C solvent: DMSO concentration: 8mM
Selfassembly; Nanostructure=Hydrogel; Gel consists of fibril structure; Trigger=temperature: 60 °C; solvent: DMSO; concentration: 8mM
Transmission Electron Microscopy (TEM), CD (Circular Dichroism spectroscopy) and NMR
Selfassembly
Record 2 Selfassembly

Source

16029045
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Hydrogel Transparent gel
solvent: 95%water+ 5% DMSO concentration: 10mM
Selfassembly; Nanostructure=Hydrogel; Transparent gel; Trigger=solvent: 95%water+ 5% DMSO; concentration: 10mM
Transmission Electron Microscopy (TEM), Scanning Electron Microscopy (SEM) and CD (Circular Dichroism spectroscopy)
Selfassembly
Evidence Records 3 records
Evidence 1 Activity

Activity

Blood-Brain Barrier
22.60%

Assay & Model

Origin/Source
BUI

Source & Reference

NA
B3Pdb

Other

SMILES
Intracarotid injection
Permeability
35-S
Evidence 2 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Hydrogel Gel consists of fibril structure Trigger=temperature: 60 °C solvent: DMSO concentration: 8mM
Hydrogel Gel consists of fibril structure

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

None specified
temperature: 60 °C solvent: DMSO concentration: 8mM
Transmission Electron Microscopy (TEM), CD (Circular Dichroism spectroscopy) and NMR
11457225
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
Evidence 3 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Hydrogel Transparent gel Trigger=solvent: 95%water+ 5% DMSO concentration: 10mM
Hydrogel Transparent gel

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

None specified
solvent: 95%water+ 5% DMSO concentration: 10mM
Transmission Electron Microscopy (TEM), Scanning Electron Microscopy (SEM) and CD (Circular Dichroism spectroscopy)
16029045
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
Additional Detail Fields 6 fields
temperature: 60 °C solvent: DMSO concentration: 8mM solvent: 95%water+ 5% DMSO concentration: 10mM
Intracarotid injection
None specified
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
11457225 16029045
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly