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Peptide record

TPDB64912

Blood-Brain Barrier Tumor-homing Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB64912
Blood-Brain Barrier Tumor-homing Peptides
Cancer-related peptides Delivery and barrier-penetrating peptides
BBPpredict Peptipedia TumorHoPe2.0
standard
No
A 9-aa standard natural multi-activity (Blood-Brain Barrier and Tumor-homing Peptides) peptide sequence curated from BBPpredict, Peptipedia, and TumorHoPe2.0, with an available 3D structural model.
Sequence
CRTIGPSVC
Physicochemical Analysis
C37H66N12O12S2
ANDEQHLKMFWY
C
935.12
8.30
1
0
2
+1
0.82
0.633
75.56
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
13.37
4
Residue Composition
number
0
A
1
R
0
N
0
D
2
C
0
E
0
Q
1
G
0
H
1
I
0
L
0
K
0
M
0
F
1
P
1
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 0 K: 0 M: 0 F: 0 P: 1 S: 1 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
9
C37H66N12O12S2
935.12
8.30
+1
0.82
0.633
Evidence Records 2 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor vessel, Tumor cell, Endothelial cell
Targeting
Glioma
αvβ3, αvβ5

Source & Reference

TumorHoPe2.0
TumorHoPe2
Methods and compositions related to adenoassociated virus-phage particles
2017
US 9827327 B2
US 9827327 B2

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
U87 human-derived glioblastoma cell, prostate DU145 carcinoma cells, Human umbilical vein endothelial cells (HUVEC), M21 human melanoma cells
BALB/c nude mice
Synthetic
glycoproteins, FITC
cyclic peptide, a bicyclic, and/or a linear
Evidence 2 Activity

Activity

Tumor-homing Peptides

Target

Tumor vessel, Tumor cell, Endothelial cell
Targeting
Glioma
αvβ3, αvβ5

Source & Reference

TumorHoPe2.0
TumorHoPe2
Methods and compositions related to adenoassociated virus-phage particles
2017
US 9827327 B2
US 9827327 B2

Other

U87 human-derived glioblastoma cell, prostate DU145 carcinoma cells, Human umbilical vein endothelial cells (HUVEC), M21 human melanoma cells
BALB/c nude mice
Synthetic
glycoproteins, FITC
Additional Detail Fields 3 fields
glycoproteins, FITC
U87 human-derived glioblastoma cell, prostate DU145 carcinoma cells, Human umbilical vein endothelial cells (HUVEC), M21 human melanoma cells
BALB/c nude mice