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Peptide record

TPDB64872

AH-D Blood-Brain Barrier standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB64872
AH-D
Blood-Brain Barrier
Delivery and barrier-penetrating peptides
B3Pred BBPpredict Peptipedia
standard
No
A 27-aa standard natural blood-brain barrier peptide sequence curated from B3Pred, BBPpredict, and Peptipedia, with an available 3D structural model.
Sequence
SGSWLRDVWDWICTVLTDFKTWLQSKL
Physicochemical Analysis
C154H227N37O41S1
ANEHMPY
LW
3284.78
6.32
3
3
12
-0
-3.30
-0.052
93.70
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
22000
669.76
8
Residue Composition
number
0
A
1
R
0
N
3
D
1
C
0
E
1
Q
1
G
0
H
1
I
4
L
2
K
0
M
1
F
0
P
3
S
3
T
4
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 3 C: 1 E: 0 Q: 1 G: 1 H: 0 I: 1 L: 4 K: 2 M: 0 F: 1 P: 0 S: 3 T: 3 W: 4 Y: 0 V: 2
Chemical Descriptors
27
C154H227N37O41S1
3284.78
6.32
-0
-3.30
-0.052
Linear
Similarity
Ser-Gly-Ser-Trp-Leu-Arg-Asp-Val-Trp-Asp-Trp-Ile-Cys-Thr-Val-Leu-Thr-Asp-Phe-Lys-Thr-Trp-Leu-Gln-Ser-Lys-Leu
Evidence Records 2 records
Evidence 1 Activity

Activity

Blood-Brain Barrier
0.0003853 mL/(g x min)

Assay & Model

Origin/Source
Unidirectional influx rate constant

Source & Reference

NA
B3Pdb

Other

Chemically synthesized
Intravenous
Permeability
Evidence 2 Activity

Activity

Blood-Brain Barrier
0.0060268 ml/g

Assay & Model

Origin/Source
Initial disrobution volume

Source & Reference

NA
B3Pdb

Other

Chemically synthesized
Intravenous
Permeability
Additional Detail Fields 1 fields
Intravenous