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Peptide record

TPDB64844

L57 Blood-Brain Barrier standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB64844
L57
Blood-Brain Barrier
Delivery and barrier-penetrating peptides
B3Pred BBPpredict Peptipedia
standard
No
A 20-aa standard natural blood-brain barrier peptide sequence curated from B3Pred, BBPpredict, and Peptipedia, with an available 3D structural model.
Sequence
TWPKHFDKHTFYSILKLGKH
Physicochemical Analysis
C120H175N31O27
ARNCEQMV
K
2483.90
10.31
7
1
7
+3
2.46
-0.870
58.50
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
6990
281.41
4
Residue Composition
number
0
A
0
R
0
N
1
D
0
C
0
E
0
Q
1
G
3
H
1
I
2
L
4
K
0
M
2
F
1
P
1
S
2
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 1 H: 3 I: 1 L: 2 K: 4 M: 0 F: 2 P: 1 S: 1 T: 2 W: 1 Y: 1 V: 0
Chemical Descriptors
20
C120H175N31O27
2483.90
10.31
+3
2.46
-0.870
Linear
Similarity
Thr-Trp-Pro-Lys-His-Phe-Asp-Lys-His-Thr-Phe-Tyr-Ser-Ile-Leu-Lys-Leu-Gly-Lys-His
Evidence Records 2 records
Evidence 1 Activity

Activity

Blood-Brain Barrier
0.22 %/g

Assay & Model

Origin/Source
% injected dose

Source & Reference

NA
B3Pdb

Other

Hemoglobin
In situ perfusion (single time)
Permeability
Direct iodination
Evidence 2 Activity

Activity

Blood-Brain Barrier
0.042 %/g

Assay & Model

Origin/Source
% injected dose

Source & Reference

NA
B3Pdb

Other

Hemoglobin
Intravenous
Permeability
Direct iodination
Additional Detail Fields 1 fields
In situ perfusion (single time) Intravenous