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Peptide record

TPDB64825

Adiponetic peptide Blood-Brain Barrier standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB64825
Adiponetic peptide
Blood-Brain Barrier
Delivery and barrier-penetrating peptides
B3Pred BBPpredict Peptipedia
standard
No
A 18-aa standard natural blood-brain barrier peptide sequence curated from B3Pred, BBPpredict, and Peptipedia, with an available 3D structural model.
Sequence
LQVYGDGDHNGLYADNVN
Physicochemical Analysis
C84H122N24O31
RCEIKMFPSTW
NDG
1964.03
3.59
1
3
7
-3
3.49
-0.761
81.11
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
2980
151.73
6
Residue Composition
number
1
A
0
R
3
N
3
D
0
C
0
E
1
Q
3
G
1
H
0
I
2
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
2
Y
2
V
Amino Acid Distribution
A: 1 R: 0 N: 3 D: 3 C: 0 E: 0 Q: 1 G: 3 H: 1 I: 0 L: 2 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 2 V: 2
Chemical Descriptors
18
C84H122N24O31
1964.03
3.59
-3
3.49
-0.761
Linear
Similarity
Evidence Records 1 records
Evidence 1 Activity

Activity

Blood-Brain Barrier
APNp promoted neural sur- vival following ICH injury in the diabetic setting, by suppressing mitocho

Assay & Model

Origin/Source
15 mg/kg of APNp
Fourier Transform Infrared Spectroscopy
APNp suppressed mitochondrial and ATF4-CHOP apoptosis pathways in a Smad3 dependent manner.
ICH injury in diabetic mice

Source & Reference

NA
B3Pdb

Other

Intraperitoneal
Permeability
Alone
Additional Detail Fields 1 fields
Intraperitoneal