Peptide record

TPDB64788

Scr-G23 Blood-Brain Barrier standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB64788
Scr-G23
Blood-Brain Barrier
Delivery and barrier-penetrating peptides
B3Pred BBPpredict Peptipedia
standard
No
A 12-aa standard natural blood-brain barrier peptide sequence curated from B3Pred, BBPpredict, and Peptipedia, with an available 3D structural model.
Sequence
KISHLLNYRTWL
Physicochemical Analysis
C73H114N20O17
ADCEQGMFPV
L
1543.83
10.42
3
0
6
+2
-1.33
-0.242
130.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
6990
452.77
4
Residue Composition
number
0
A
1
R
1
N
0
D
0
C
0
E
0
Q
0
G
1
H
1
I
3
L
1
K
0
M
0
F
0
P
1
S
1
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 1 L: 3 K: 1 M: 0 F: 0 P: 0 S: 1 T: 1 W: 1 Y: 1 V: 0
Chemical Descriptors
12
C73H114N20O17
1543.83
10.42
+2
-1.33
-0.242
Linear
Similarity
LysIleSerHisLeuLeuAsnTyrArgThrTrpLeu
Evidence Records 2 records
Evidence 1 Activity

Activity

Blood-Brain Barrier

Assay & Model

Origin/Source
Radioimaging
0.013 + 0.006 of fluoroscent measured in btain tissue after 4 hours

Source & Reference

NA
B3Pdb

Other

Phage display of prion proteins
Intravenous
Transcytosis as well as BBB penetration
Evidence 2 Activity

Activity

Blood-Brain Barrier

Assay & Model

Origin/Source
Radioimaging
0.008 + 0.002 of fluoroscent measured in btain tissue after 24 hours

Source & Reference

NA
B3Pdb

Other

Phage display of prion proteins
Intravenous
Transcytosis as well as BBB penetration
Additional Detail Fields 1 fields
Intravenous