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Peptide record

TPDB64708

Opiorphin Blood-Brain Barrier standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB64708
Opiorphin
Blood-Brain Barrier
Delivery and barrier-penetrating peptides
B3Pred BBPpredict Peptipedia
standard
No
A 5-aa standard natural blood-brain barrier peptide sequence curated from B3Pred, BBPpredict, and Peptipedia, with an available 3D structural model.
Sequence
QRFSR
Physicochemical Analysis
C29H48N12O8
ANDCEGHILKMPTWYV
R
692.78
12.40
2
0
1
+2
1.20
-2.100
0.00
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
0
0.00
2
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
0
I
0
L
0
K
0
M
1
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 1 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
5
C29H48N12O8
692.78
12.40
+2
1.20
-2.100
Linear
Similarity
Gln-Arg-Phe-Ser-Arg
N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Blood-Brain Barrier
0.00000053 cm/s

Assay & Model

Initial concentration in donor chamber-Culture
Origin/Source
Parallel artificial membrane permeation assay apparent permiability cofficient

Source & Reference

NA
B3Pdb

Other

Chemically synthesized
Saturable