Back to search

Peptide record

TPDB64676

YTA2 Cell-penetrating Peptides standard
16 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB64676
YTA2
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 16-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Conjugation with fluorescein
Sequence
YTAIAWVKAFIRKLRK-NH2
Physicochemical Analysis
C95H154N26O19
NDCEQGHMPS
AK
1964.43
11.59
5
0
10
+5
-0.81
0.100
110.00
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
6990
355.83
2
Residue Composition
number
3
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
1
L
3
K
0
M
1
F
0
P
0
S
1
T
1
W
1
Y
1
V
Amino Acid Distribution
A: 3 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 1 K: 3 M: 0 F: 1 P: 0 S: 0 T: 1 W: 1 Y: 1 V: 1
Chemical Descriptors
16
C95H154N26O19
1964.43
11.59
+5
-0.81
0.100
Amidation
L
Linear
Conjugation with fluorescein
N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

MDA-MB-231

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Fluorophore (fluorescein)
In vitro
CCSSHHHHHHHTTTTC
Additional Detail Fields 1 fields
CCSSHHHHHHHTTTTC