Back to search

Peptide record

TPDB64661

PN282 (SEQ ID NO: 78) Cell-penetrating Peptides standard
13 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB64661
PN282 (SEQ ID NO: 78)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 13-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Maleimide addition
Sequence
YRFKYRFKYRLFK-NH2
Physicochemical Analysis
C96H139N25O17
ANDCEQGHIMPSTWV
RKFY
1915.32
10.99
6
0
7
+6
-1.37
-1.300
30.00
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
4470
233.38
3
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
3
K
0
M
3
F
0
P
0
S
0
T
0
W
3
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 3 M: 0 F: 3 P: 0 S: 0 T: 0 W: 0 Y: 3 V: 0
Chemical Descriptors
13
C96H139N25O17
1915.32
10.99
+6
-1.37
-1.300
Amidation
L
Linear
Maleimide addition
N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

9 L/LacZ cells

Source & Reference

CPPsite3.0
CPPsite3
US 20060035815

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Nucleic acid (siRNA)
In vitro
CCSTTTTTCCSCC
Additional Detail Fields 1 fields
CCSTTTTTCCSCC