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Peptide record

TPDB64660

PN267 (SEQ ID NO: 77) Blood-Brain Barrier Cell-penetrating Peptides standard
4 amino acids
Basic Information
3D PDB MODEL
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TPDB64660
PN267 (SEQ ID NO: 77)
Blood-Brain Barrier Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
Peptipedia CellPPD CellPPD-MOD CPPsite3.0
standard
No
A 4-aa standard natural multi-activity (Blood-Brain Barrier and Cell-penetrating Peptides) peptide sequence curated from Peptipedia, CellPPD, CellPPD-MOD, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Maleimide addition
Sequence
YRFK-NH2
Physicochemical Analysis
C30H44N8O6
ANDCEQGHILMPSTWV
RKFY
612.73
10.42
2
0
2
+2
-0.27
-1.725
0.00
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
1490
243.17
1
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
1
K
0
M
1
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 1 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
4
C30H44N8O6
612.73
10.42
+2
-0.27
-1.725
Amidation
L
Linear
Maleimide addition
N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

9 L/LacZ cells

Source & Reference

CPPsite3.0
CPPsite3
US 20060035815

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Nucleic acid (siRNA)
In vitro
CCCC
Additional Detail Fields 1 fields
CCCC