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Peptide record

TPDB64652

Leptin30 Blood-Brain Barrier Cell-penetrating Peptides standard
30 amino acids
Basic Information
3D PDB MODEL
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TPDB64652
Leptin30
Blood-Brain Barrier Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
BBPpredict Peptipedia CPPsite3.0
standard
No
A 30-aa standard natural multi-activity (Blood-Brain Barrier and Cell-penetrating Peptides) peptide sequence curated from BBPpredict, Peptipedia, and CPPsite3.0, with an available 3D structural model.
Sequence
YQQILTSMPSRNVIQISNDLENLRDLLHVL
Physicochemical Analysis
C154H256N44O48S1
ACGKFW
L
3524.05
5.28
3
3
13
-1
5.72
-0.103
136.33
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
1490
42.28
11
Residue Composition
number
0
A
2
R
3
N
2
D
0
C
1
E
3
Q
0
G
1
H
3
I
6
L
0
K
1
M
0
F
1
P
3
S
1
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 0 R: 2 N: 3 D: 2 C: 0 E: 1 Q: 3 G: 0 H: 1 I: 3 L: 6 K: 0 M: 1 F: 0 P: 1 S: 3 T: 1 W: 0 Y: 1 V: 2
Chemical Descriptors
30
C154H256N44O48S1
3524.05
5.28
-1
5.72
-0.103
Free
L
Linear
Free
N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

hCMEC/D3, Hek293T

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
AAV serotype 9 (AAV9) encoding GFP
GFP-expressing cells increased about 230% compared to AAV11 alone
In vitro
CCSSSCCTTCCCCCSCC
Additional Detail Fields 1 fields
CCSSSCCTTCCCCCSCC