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Peptide record

TPDB64643

RBD-1 (CPP5) Cell-penetrating Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB64643
RBD-1 (CPP5)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 15-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
YLNSSLYRGTKFIIK
Physicochemical Analysis
C85H135N21O22
ADCEQHMPWV
ILKSY
1803.13
10.36
3
0
7
+3
-1.13
-0.113
104.00
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
2980
165.27
6
Residue Composition
number
0
A
1
R
1
N
0
D
0
C
0
E
0
Q
1
G
0
H
2
I
2
L
2
K
0
M
1
F
0
P
2
S
1
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 2 L: 2 K: 2 M: 0 F: 1 P: 0 S: 2 T: 1 W: 0 Y: 2 V: 0
Chemical Descriptors
15
C85H135N21O22
1803.13
10.36
+3
-1.13
-0.113
Free
L
Linear
Free
N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCSC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

B16-F10 Cells , PC-12 Cells ,B16-F10 And Human Dermal Fibroblasts (Hdfs)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
FITC at N terminal
CPP-5 displayed the highest cellular uptake at 52.7%
In vitro
CCGGGTSCCCCCC
Additional Detail Fields 1 fields
CCGGGTSCCCCCC