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Peptide record

TPDB64642

CPP7 Cell-penetrating Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB64642
CPP7
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 15-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation N-terminal: Acetylation
Sequence
Ac-YLKFIPLKRAIWLIK-NH2
Physicochemical Analysis
C97H156N22O17
NDCEQGHMSTV
ILK
1902.44
10.91
4
0
10
+4
-2.47
0.633
162.67
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
6990
367.42
1
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
3
I
3
L
3
K
0
M
1
F
1
P
0
S
0
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 3 L: 3 K: 3 M: 0 F: 1 P: 1 S: 0 T: 0 W: 1 Y: 1 V: 0
Chemical Descriptors
15
C97H156N22O17
1902.44
10.91
+4
-2.47
0.633
Amidation
L
Linear
Acetylation
N[C@@H](CCSC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

PBMCs, Cd19+ B Cells, Cd14+ Monocytes, And Bdca2+Cd123+ Plasmacytoid Dendritic Cells (Pdcs), HeLa And THP-1 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
FITC dye
In vitro
CHHHHHCCCCSSSSSCCCC
Additional Detail Fields 1 fields
CHHHHHCCCCSSSSSCCCC