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Peptide record

TPDB64632

Pep7 Cell-penetrating Peptides modified_plain modified
13 amino acids
Basic Information
3D PDB MODEL
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TPDB64632
Pep7
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
modified_plain
Yes
A 13-aa modified cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation Chemical: X = Dipropylglycine (Dpg), N-terminal tyrosine (Tyr) N-terminal: Acetylation
Sequence
Ac-YKLKXLKLXLLKX-NH2
Physicochemical Analysis
C63H114N14O12
ARNDCEQGHIMFPSTWV
L
1259.68
10.64
4
0
6
+4
0.22
0.162
150.00
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
1490
118.28
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
5
L
4
K
0
M
0
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 5 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
13
C63H114N14O12
1259.68
10.64
+4
0.22
0.162
Amidation
X = Dipropylglycine (Dpg), N-terminal tyrosine (Tyr)
Modified
Linear
Acetylation
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Huh-7 And HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear Modified
Synthetic
Cy5-labeled pDNA (fLuc and gLuc)
In vitro