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Peptide record

TPDB64628

YKA peptide Cell-penetrating Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB64628
YKA peptide
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 12-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, MLCPP 2.0, Peptipedia, and other sources, with an available 3D structural model.
Chemical: Histidine tagged
Sequence
YKALRISRKLAK
Physicochemical Analysis
C66H119N21O15
NDCEQGHMFPTWV
K
1446.80
11.59
5
0
6
+5
2.01
-0.592
114.17
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
1490
102.99
2
Residue Composition
number
2
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
2
L
3
K
0
M
0
F
0
P
1
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 2 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 2 K: 3 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
12
C66H119N21O15
1446.80
11.59
+5
2.01
-0.592
Free
Histidine tagged
L
Linear
Free
N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Skin with Franz diffusion cells

Assay & Model

Porcine ear skin
Porcine ear skin

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Nanoparticles [Nanostructured lipid carriers (NLC) and Ibuprofen (Ibu)]
In vitro
CCSCCCCTTCCC
Additional Detail Fields 1 fields
CCSCCCCTTCCC