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Peptide record

TPDB64610

Mutant tat-NBD Cell-penetrating Peptides standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB64610
Mutant tat-NBD
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 21-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, MLCPP 2.0, Peptipedia, and other sources, with an available 3D structural model.
Sequence
YGRKKRRQRRTALDASALQTE
Physicochemical Analysis
C104H182N40O32
NCHIMFPWV
R
2504.84
11.85
7
2
6
+5
8.29
-1.676
51.43
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
1490
59.48
6
Residue Composition
number
3
A
5
R
0
N
1
D
0
C
1
E
2
Q
1
G
0
H
0
I
2
L
2
K
0
M
0
F
0
P
1
S
2
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 3 R: 5 N: 0 D: 1 C: 0 E: 1 Q: 2 G: 1 H: 0 I: 0 L: 2 K: 2 M: 0 F: 0 P: 0 S: 1 T: 2 W: 0 Y: 1 V: 0
Chemical Descriptors
21
C104H182N40O32
2504.84
11.85
+5
8.29
-1.676
L
Linear
Free
N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(=O)O)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Assay & Model

Wistar rat pups
Wistar rat pups

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
In vivo
CTTCHHHHCCSSSTTSCTTCC
Additional Detail Fields 1 fields
CTTCHHHHCCSSSTTSCTTCC