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Peptide record

TPDB64609

SP-Tatm3xCherry Cell-penetrating Peptides standard
33 amino acids
Basic Information
3D PDB MODEL
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TPDB64609
SP-Tatm3xCherry
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 33-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, Peptipedia, and PerseuCPP, with an available 3D structural model.
C-terminal: Conjugation with mCherry N-terminal: Coupled to signal peptide
Sequence
YGRKKRRQRRRYGRKKRRQRRRYGRKKRRQRRR
Physicochemical Analysis
C192H350N96O40
ANDCEHILMFPSTWV
R
4643.51
12.95
24
0
3
+24
19.47
-3.636
0.00
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
4470
96.26
6
Residue Composition
number
0
A
18
R
0
N
0
D
0
C
0
E
3
Q
3
G
0
H
0
I
0
L
6
K
0
M
0
F
0
P
0
S
0
T
0
W
3
Y
0
V
Amino Acid Distribution
A: 0 R: 18 N: 0 D: 0 C: 0 E: 0 Q: 3 G: 3 H: 0 I: 0 L: 0 K: 6 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 3 V: 0
Chemical Descriptors
33
C192H350N96O40
4643.51
12.95
+24
19.47
-3.636
Conjugation with mCherry
L
Amphipathic
Linear
Coupled to signal peptide
N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

H1299, A549 and CHO-K1

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Synthetic
Fluorophore (mCherry)
ER and Cytoplasm
High
Classical Pathway
In vitro
CCSCHHHHTTTCCTTHHHHTTTCCTTGGGSCCC
Additional Detail Fields 1 fields
CCSCHHHHTTTCCTTHHHHTTTCCTTGGGSCCC