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Peptide record

TPDB64608

Tat-GFP-Tat Cell-penetrating Peptides standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB64608
Tat-GFP-Tat
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 22-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, Peptipedia, and PerseuCPP, with an available 3D structural model.
Sequence
YGRKKRRQRRRYGRKKRRQRRR
Physicochemical Analysis
C128H234N64O27
ANDCEHILMFPSTWV
R
3101.68
12.88
16
0
2
+16
12.98
-3.636
0.00
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
2980
96.08
4
Residue Composition
number
0
A
12
R
0
N
0
D
0
C
0
E
2
Q
2
G
0
H
0
I
0
L
4
K
0
M
0
F
0
P
0
S
0
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 0 R: 12 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 2 H: 0 I: 0 L: 0 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 2 V: 0
Chemical Descriptors
22
C128H234N64O27
3101.68
12.88
+16
12.98
-3.636
Free
L
Linear
Free
N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

PC-3 cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Protein (eGFP)
Unable to penetrate PC-3 cells at 100 nM concentartion
Endocytic pathway
In vitro
CCSCGGGGGGTCCTTGGGCCCC
Additional Detail Fields 1 fields
CCSCGGGGGGTCCTTGGGCCCC