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Peptide record

TPDB64605

TAT-mGluR1 Blood-Brain Barrier Cell-penetrating Peptides standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB64605
TAT-mGluR1
Blood-Brain Barrier Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
B3Pred BBPpredict Peptipedia CPPsite3.0
standard
No
A 25-aa standard natural multi-activity (Blood-Brain Barrier and Cell-penetrating Peptides) peptide sequence curated from B3Pred, BBPpredict, Peptipedia, and other sources, with an available 3D structural model.
Chemical: FITC-labeled
Sequence
YGRKKRRQRRRVIKPLTKSYQGSGK
Physicochemical Analysis
C132H232N50O33
ANDCEHMFW
R
3047.61
12.42
11
0
5
+11
9.17
-1.948
42.80
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
2980
97.78
7
Residue Composition
number
0
A
6
R
0
N
0
D
0
C
0
E
2
Q
3
G
0
H
1
I
1
L
5
K
0
M
0
F
1
P
2
S
1
T
0
W
2
Y
1
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 3 H: 0 I: 1 L: 1 K: 5 M: 0 F: 0 P: 1 S: 2 T: 1 W: 0 Y: 2 V: 1
Chemical Descriptors
25
C132H232N50O33
3047.61
12.42
+11
9.17
-1.948
Free
FITC-labeled
L
Linear
Free
N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Assay & Model

Male Sprague-Dawley (SD) rat SAH model
Male Sprague-Dawley (SD) rat SAH model

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Fusogenic
Metabotropic glutamate receptor 1 (mGluR1)
In vivo
CCSCSGGGGTCSSSCCCCCCC
Additional Detail Fields 1 fields
CCSCSGGGGTCSSSCCCCCCC