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Peptide record

TPDB64602

TP95414 Cell-penetrating Peptides standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB64602
TP95414
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 25-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
YGRKKRRQRRRSSLGSGTASLRSNP
Physicochemical Analysis
C117H208N50O35
DCEHIMFWV
R
2875.25
12.80
9
0
4
+9
7.69
-1.828
35.20
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
1490
51.82
9
Residue Composition
number
1
A
7
R
1
N
0
D
0
C
0
E
1
Q
3
G
0
H
0
I
2
L
2
K
0
M
0
F
1
P
5
S
1
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 7 N: 1 D: 0 C: 0 E: 0 Q: 1 G: 3 H: 0 I: 0 L: 2 K: 2 M: 0 F: 0 P: 1 S: 5 T: 1 W: 0 Y: 1 V: 0
Chemical Descriptors
25
C117H208N50O35
2875.25
12.80
+9
7.69
-1.828
Free
L
Linear
Free
N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Rat Cortical Neurons

Assay & Model

Adult male Balb/cOlaHsd mice
Adult male Balb/cOlaHsd mice

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
PSD-95 sequences (TP95414 aa 414-427)
In vitro and in vivo
CCCCCC
Additional Detail Fields 1 fields
CCCCCC