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Peptide record

TPDB64587

TP95(29) Cell-penetrating Peptides standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB64587
TP95(29)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 25-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
YGRKKRRQRRRLPNQANSPPVIVNT
Physicochemical Analysis
C128H222N50O34
DCEHMFW
R
3005.49
12.71
8
0
6
+8
9.05
-1.672
58.40
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
1490
49.58
8
Residue Composition
number
1
A
6
R
3
N
0
D
0
C
0
E
2
Q
1
G
0
H
1
I
1
L
2
K
0
M
0
F
3
P
1
S
1
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 1 R: 6 N: 3 D: 0 C: 0 E: 0 Q: 2 G: 1 H: 0 I: 1 L: 1 K: 2 M: 0 F: 0 P: 3 S: 1 T: 1 W: 0 Y: 1 V: 2
Chemical Descriptors
25
C128H222N50O34
3005.49
12.71
+8
9.05
-1.672
Free
L
Linear
Free
NCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCSC)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Rat Cortical Neurons

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
PSD-95 sequences (PSD-95 aa 29-42)
In vitro
CCCBTTBCCCCSSCCCCCCCSSCCCCC
Additional Detail Fields 1 fields
CCCBTTBCCCCSSCCCCCCCSSCCCCC