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Peptide record

TPDB64584

TAT-LAH4 Cell-penetrating Peptides standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB64584
TAT-LAH4
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 37-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: CaM (Calmodulin) Attached N-terminal: Conjugation with 6 His-Tag
Sequence
YGRKKRRQRRRKKALLALALHHLAHLALHLALALKKA
Physicochemical Analysis
C196H344N70O40
NDCEIMFPSTWV
L
4321.33
12.71
16
0
19
+12
7.33
-0.432
127.03
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
1490
34.48
2
Residue Composition
number
8
A
6
R
0
N
0
D
0
C
0
E
1
Q
1
G
4
H
0
I
10
L
6
K
0
M
0
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 8 R: 6 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 4 I: 0 L: 10 K: 6 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
37
C196H344N70O40
4321.33
12.71
+12
7.33
-0.432
CaM (Calmodulin) Attached
L
Cationic
Linear
Conjugation with 6 His-Tag
N[C@@H](Cc1ccccc1)C(=O)/N=C/C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Bhk And Hek-293 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Chimeric
MBP-CBS protein
Efficient internalization
In vitro
CCTTSSCCCCC
Additional Detail Fields 1 fields
CCTTSSCCCCC