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Peptide record

TPDB64575

TV159-172 (TAT and VDAC1) Cell-penetrating Peptides standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB64575
TV159-172 (TAT and VDAC1)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 26-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: Glycine linker
Sequence
YGRKKRRQRRRGTSKSRVTQSNFAVG
Physicochemical Analysis
C128H223N53O36
DCEHILMPW
R
3080.51
12.80
10
0
5
+10
8.82
-1.808
26.15
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
1490
48.37
9
Residue Composition
number
1
A
7
R
1
N
0
D
0
C
0
E
2
Q
3
G
0
H
0
I
0
L
3
K
0
M
1
F
0
P
3
S
2
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 1 R: 7 N: 1 D: 0 C: 0 E: 0 Q: 2 G: 3 H: 0 I: 0 L: 0 K: 3 M: 0 F: 1 P: 0 S: 3 T: 2 W: 0 Y: 1 V: 2
Chemical Descriptors
26
C128H223N53O36
3080.51
12.80
+10
8.82
-1.808
Free
Glycine linker
L
Linear
Free
N[C@@H](Cc1ccccc1)C(=O)/N=C/C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Assay & Model

Sprague-Dawley rats (50-55 days old) and Brown-Norway rats ( aged 22-28, 36-42, or 50-56 days-old)
Sprague-Dawley rats (50-55 days old) and Brown-Norway rats ( aged 22-28, 36-42, or 50-56 days-old)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
VDAC1 peptide
In vivo
CCTTSSCCCCC
Additional Detail Fields 1 fields
CCTTSSCCCCC