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Peptide record

TPDB64570

TAT-Aur Cell-penetrating Peptides standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB64570
TAT-Aur
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 24-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: CaM (Calmodulin) Attached N-terminal: Conjugation with 6 His-Tag
Sequence
YGRKKRRQRRRGLFDIIKKIAESF
Physicochemical Analysis
C135H229N47O32
NCHMPTWV
R
3022.60
12.13
10
2
8
+8
7.94
-1.304
69.17
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
1490
49.30
3
Residue Composition
number
1
A
6
R
0
N
1
D
0
C
1
E
1
Q
2
G
0
H
3
I
1
L
4
K
0
M
2
F
0
P
1
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 6 N: 0 D: 1 C: 0 E: 1 Q: 1 G: 2 H: 0 I: 3 L: 1 K: 4 M: 0 F: 2 P: 0 S: 1 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
24
C135H229N47O32
3022.60
12.13
+8
7.94
-1.304
CaM (Calmodulin) Attached
L
Cationic
Linear
Conjugation with 6 His-Tag
N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Bhk And Hek-293 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Chimeric
MBP-CBS protein
Marginally effective internalization
In vitro
CCCSSCSCC
Additional Detail Fields 1 fields
CCCSSCSCC