Back to search

Peptide record

TPDB64566

Tat-beclin1 Cell-penetrating Peptides standard
31 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB64566
Tat-beclin1
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 31-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
YGRKKRRQRRRGGTNVFNATFEIWHDGEFGT
Physicochemical Analysis
C164H251N57O45
CLMPS
R
3741.15
11.77
9
3
8
+5
8.37
-1.497
25.16
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
6990
186.84
7
Residue Composition
number
1
A
6
R
2
N
1
D
0
C
2
E
1
Q
5
G
1
H
1
I
0
L
2
K
0
M
3
F
0
P
0
S
3
T
1
W
1
Y
1
V
Amino Acid Distribution
A: 1 R: 6 N: 2 D: 1 C: 0 E: 2 Q: 1 G: 5 H: 1 I: 1 L: 0 K: 2 M: 0 F: 3 P: 0 S: 0 T: 3 W: 1 Y: 1 V: 1
Chemical Descriptors
31
C164H251N57O45
3741.15
11.77
+5
8.37
-1.497
Free
L
Linear
Free
N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Neurons Dissociated From E16.5 Sd Rats

Assay & Model

Adult mice (8–10 wk) expressing fluorescent proteins (Thy1-YFP and Emx1-Cre Ai9)
Adult mice (8–10 wk) expressing fluorescent proteins (Thy1-YFP and Emx1-Cre Ai9)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Fusogenic
In vitro and in vivo
CCSCGGGCHHHHHHHHTTTCCCCCC
Additional Detail Fields 1 fields
CCSCGGGCHHHHHHHHTTTCCCCCC