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Peptide record

TPDB64565

TAT-HezK I Cell-penetrating Peptides standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB64565
TAT-HezK I
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 22-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
YGRKKRRQRRRGGGGSYFSPWG-NH2
Physicochemical Analysis
C114H178N44O28
ANDCEHILMTV
RG
2612.95
12.41
8
0
4
+8
3.33
-2.027
0.00
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
8480
324.54
5
Residue Composition
number
0
A
6
R
0
N
0
D
0
C
0
E
1
Q
6
G
0
H
0
I
0
L
2
K
0
M
1
F
1
P
2
S
0
T
1
W
2
Y
0
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 6 H: 0 I: 0 L: 0 K: 2 M: 0 F: 1 P: 1 S: 2 T: 0 W: 1 Y: 2 V: 0
Chemical Descriptors
22
C114H178N44O28
2612.95
12.41
+8
3.33
-2.027
Amidation
L
Linear
Free
N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)NCC(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Assay & Model

Nicotiana tabacum cv. K326 strain and H. armigera larvae
Nicotiana tabacum cv. K326 strain and H. armigera larvae

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
HezK I peptide
In vivo
CCSCGGGSSSCCSSSCCCCCCC
Additional Detail Fields 1 fields
CCSCGGGSSSCCSSSCCCCCCC