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Peptide record

TPDB64564

PN204 (SEQ ID NO: 42) Cell-penetrating Peptides standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB64564
PN204 (SEQ ID NO: 42)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 25-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
YGRKKRRQRRRGCYGRKKRRQRRRG-NH2
Physicochemical Analysis
C135H245N67O30S1
ANDEHILMFPSTWV
R
3318.92
12.71
16
0
2
+16
12.76
-3.132
0.00
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
2980
89.79
5
Residue Composition
number
0
A
12
R
0
N
0
D
1
C
0
E
2
Q
4
G
0
H
0
I
0
L
4
K
0
M
0
F
0
P
0
S
0
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 0 R: 12 N: 0 D: 0 C: 1 E: 0 Q: 2 G: 4 H: 0 I: 0 L: 0 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 2 V: 0
Chemical Descriptors
25
C135H245N67O30S1
3318.92
12.71
+16
12.76
-3.132
Amidation
L
Linear
Free
N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

9 L/LacZ cells

Source & Reference

CPPsite3.0
CPPsite3
US 20060035815

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Nucleic acid (siRNA)
In vitro
CCSCGGGGGGSCCCCCGGGGGGCCC
Additional Detail Fields 1 fields
CCSCGGGGGGSCCCCCGGGGGGCCC