Back to search

Peptide record

TPDB64560

TatNep Cell-penetrating Peptides standard
14 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB64560
TatNep
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 14-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: neprilysin recognition sequence (Nep) N-terminal: Conjugated with TAMRA
Sequence
YGRKKRRQRRRFFG
Physicochemical Analysis
C84H139N35O17
ANDCEHILMPSTWV
R
1911.25
12.71
8
0
3
+8
4.24
-2.486
0.00
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
1490
77.96
2
Residue Composition
number
0
A
6
R
0
N
0
D
0
C
0
E
1
Q
2
G
0
H
0
I
0
L
2
K
0
M
2
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 2 H: 0 I: 0 L: 0 K: 2 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
14
C84H139N35O17
1911.25
12.71
+8
4.24
-2.486
Free
neprilysin recognition sequence (Nep)
L
Linear
Conjugated with TAMRA
N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(=O)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(=O)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCSC)C(=O)N[C@@H](Cc1ccccc1)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

S. Cerevisiae (Mata And Matα ), Hek293T , Hek293T-Nep And HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
TAMRA dye
In vitro
CCCCSCCCSSCSSSCCCSSCCCSSSSCCCCCCCSSCC
Additional Detail Fields 1 fields
CCCCSCCCSSCSSSCCCSSCCCSSSSCCCCCCCSSCC