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Peptide record

TPDB64557

TP95(259) Cell-penetrating Peptides standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB64557
TP95(259)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 37-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
YGRKKRRQRRRDITTSYSQHLDNEISHSSYLGTDYPT
Physicochemical Analysis
C191H302N64O62
ACMFWV
R
4486.89
10.26
10
4
8
+4
12.23
-1.716
42.16
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
5960
132.83
16
Residue Composition
number
0
A
6
R
1
N
3
D
0
C
1
E
2
Q
2
G
2
H
2
I
2
L
2
K
0
M
0
F
1
P
5
S
4
T
0
W
4
Y
0
V
Amino Acid Distribution
A: 0 R: 6 N: 1 D: 3 C: 0 E: 1 Q: 2 G: 2 H: 2 I: 2 L: 2 K: 2 M: 0 F: 0 P: 1 S: 5 T: 4 W: 0 Y: 4 V: 0
Chemical Descriptors
37
C191H302N64O62
4486.89
10.26
+4
12.23
-1.716
Free
L
Linear
Free
N[C@@H](CS)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CS)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Rat Cortical Neurons

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
PSD-95 sequences (TP95259 aa 259-284)
In vitro
CCHHHHGGGCC
Additional Detail Fields 1 fields
CCHHHHGGGCC