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Peptide record

TPDB64481

W3K4W3-E8 Cell-penetrating Peptides standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB64481
W3K4W3-E8
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 18-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Nanoparticles Attached N-terminal: Conjugated with FITC
Sequence
WWWKKKKWWWEEEEEEEE
Physicochemical Analysis
C130H166N28O35
ARNDCQGHILMFPSTYV
E
2680.91
4.25
4
8
6
-4
9.02
-2.722
0.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
33000
1230.92
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
8
E
0
Q
0
G
0
H
0
I
0
L
4
K
0
M
0
F
0
P
0
S
0
T
6
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 8 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 6 Y: 0 V: 0
Chemical Descriptors
18
C130H166N28O35
2680.91
4.25
-4
9.02
-2.722
Nanoparticles Attached
L
Amphiphilic
Linear
Conjugated with FITC
N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

MCF-7

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphiphilic
Synthetic
Epirubicin (EPR)
Nucleus
100% cellular Uptake
In vitro
CCSSCSSBTTBSSSCC
Additional Detail Fields 1 fields
CCSSCSSBTTBSSSCC