Peptide record

TPDB64465

Truncated AA3H 5 Cell-penetrating Peptides standard
4 amino acids
Basic Information
3D PDB MODEL
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TPDB64465
Truncated AA3H 5
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 4-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
N-terminal: Conjugated with FITC
Sequence
WVGH
Physicochemical Analysis
C24H31N7O5
ARNDCEQILKMFPSTY
GHWV
497.55
7.85
1
0
2
+0
-0.81
-0.075
72.50
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
5500
1105.41
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
1
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
4
C24H31N7O5
497.55
7.85
+0
-0.81
-0.075
Free
L
Hydrophobic
Linear
Conjugated with FITC
N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CC1=NC=NC1)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Hydrophobic
Synthetic
FITC dye
Order of uptake is SIWV> ASIW> WVGH > IWVG
In vitro
CCC
Additional Detail Fields 1 fields
CCC