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Peptide record

TPDB64457

W₅R₄C Cell-penetrating Peptides standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB64457
W₅R₄C
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 10-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
WRWRWRWRWC
Physicochemical Analysis
C82H105N27O11S1
ANDEQGHILKMFPSTYV
W
1676.97
12.40
4
0
5
+4
-6.25
-2.000
0.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
27500
1639.86
1
Residue Composition
number
0
A
4
R
0
N
0
D
1
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
5
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 5 Y: 0 V: 0
Chemical Descriptors
10
C82H105N27O11S1
1676.97
12.40
+4
-6.25
-2.000
Free
L
Cationic
Cyclic
Free
N[C@@H](CCCCN)C(=O)N[C@H](CCC(=O)O)C(=O)N[C@@H]([C@H](C)O)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H]([C@H](C)O)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@H]([C@H](C)O)C(=O)N[C@H](CCC(=O)O)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@H](CO)C(=O)N[C@@H](CCC(=O)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(C)C)C1OO1
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

CHO Dg44 Cells, CHO-Grapfurin Cells And Ht1080 Fibrosarcoma Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Cyclic L Cationic
Synthetic
In vitro
CCSSCCCCCCCCCCCSSCCCC
Additional Detail Fields 1 fields
CCSSCCCCCCCCCCCSSCCCC