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Peptide record

TPDB64439

PN288 (SEQ ID NO: 88) Cell-penetrating Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB64439
PN288 (SEQ ID NO: 88)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia
standard
No
A 12-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Maleimide addition
Sequence
WRFKWRFKWRFK-NH2
Physicochemical Analysis
C96H131N27O13
ANDCEQGHILMPSTYV
RKFW
1871.27
12.71
6
0
6
+6
-3.54
-1.625
0.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
16500
881.75
0
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
3
K
0
M
3
F
0
P
0
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 3 M: 0 F: 3 P: 0 S: 0 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
12
C96H131N27O13
1871.27
12.71
+6
-3.54
-1.625
Amidation
L
Linear
Maleimide addition
N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

9 L/LacZ cells

Source & Reference

CPPsite3.0
CPPsite3
US 20060035815

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Nucleic acid (siRNA)
In vitro
CGGGCSSCSSCC
Additional Detail Fields 1 fields
CGGGCSSCSSCC